The deadliest infectious disease of all time is curable

Tuberculosis (TB) is the deadliest infectious disease in history, having caused more than 1 billion deaths over the past 200 years. It is currently the leading infectious killer globally, recently surpassing COVID-19 to regain this status. TB has plagued humanity for thousands of years.

And yet, it is a preventable and curable disease. Most cases of active TB can be successfully treated and cured with a standard course of antibiotics. Tuberculosis death isn’t really caused by the bacteria anymore but by social determinants of health. Something should be done.

That’s from “Everything Is Tuberculosis: The History and Persistence of Our Deadliest Infection,” a March 2025 book by American author, novelist and Youtuber John Green. It is short, charming, insightful and harrowing. I recommend reading, and joining his cause.

“The real cause of contemporary tuberculosis is, for lack of a better term, us,” he writes. “So we have entered a strange era of human history: a preventable, curable infectious disease remains are deadliest. That’s the world we are currently choosing.”

Below are my notes for future reference.

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The Anthropocene Reviewed

A novelist writes memoir in code.

That’s something Allegra Goodman said that John Green quoted as inspiration in the introduction to the essay collection he published last year. Green is the author of several novels himself, including the 2012 The Fault in our Stars that was made into a movie of the same name. I knew him first, like many other Millennial internet-dwellers, from various educational video projects on Youtube, including several with his brother.

He took on a mix nonfiction-memoir project with The Anthropocene Reviewed, which takes on a few dozen wide-ranging topics with short reviews interspersed with his own life. I enjoyed his approach and admire the author so I have no worthy review. Find one here. Instead, I say go read it. Below I captured my favorite dozen or so of the many quotations he references throughout the book.

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